Microbial Engineering

A New ECI Conference

March 4-8, 2018
Hyatt Regency Tamaya
Santa Ana Pueblo (near Albuquerque), New Mexico, USA

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Call For Abstracts

Please forward this link to colleagues who may be interested in the conference topic.

About this Conference

Advances in synthetic biology and metabolic engineering have created many new opportunities for using microbes as hosts. It has become possible to make entirely new products or to radically improve processes for making existing products not only in terms of increased production but also the enhanced quality of the outcome.

This conference will highlight the cell and process engineering required to create these new microbes and will illustrate the benefits and challenges using Case Studies. We will learn about progress from various fields, including:

  • Vaccines
  • Primary Metabolites
  • Secondary Metabolites
  • Therapeutic Proteins
  • Biofuels
  • Biopolymers

The Case Studies will further provide the opportunity to illustrate the integration of various activities such as analytics, downstream purification, scale-up, and high throughput screening in order to achieve successful commercialization.

Keynote Speakers (confirmed)

Jay Keasling (University of California-Berkeley)
Chris Love (Koch Institute at MIT)
Christina Smolke (Stanford University)
Jim Swartz (Stanford University)

Sessions

Advances in synthetic biology and metabolic engineering have created many new opportunities for using microbes as hosts. It has become possible to make entirely new products or to radically improve processes for making existing products, not only in terms of increased production but also the enhanced quality of the outcome. Our goal is to highlight recent advances in Synthetic Biology and Metabolic Engineering as well as to address the challenges for successful commercialization. These challenges include Development  and Scale-up of Fermentations, development of streamlined purification processes and rapid analytics combined with sophisticated process control.

VACCINES

Session Chairs: Barry Buckland (UCL) and Tiffany Rau  (Evonik-Degussa)

Our ability to develop targeted antigens in microbial hosts effective as vaccines steadily increases as our knowledge of biology increases.  At the same time due to increase travel, population density and climate change we see an increase in emerging disease threats to our health.  Many opportunities exist for the application of microbial hosts to make carbohydrates, proteins, DNA and RNA.

PRIMARY METABOLITES

Session Chairs: Brigitte Gasser (BOKU, Austria) and Arindam Bose (Previously Pfizer)

Traditionally excellent microbial processes have been developed to make primary metabolites such as amino acids, ethylene, and many organic acids at low cost. How is the revolution in biology impacting these traditional areas?

SECONDARY METABOLITES

Session Chairs: Yi Tang (UCLA) and Beth Junker (Bioprocess Advantage)

Natural Products such as antibiotics have been a main building block in the pharmaceutical industry for many decades. This continues with the demonstrated ability to develop much more efficient microbial based processes for manufacture of drugs such as artemesin for malaria and also opiates for pain treatment. Whole new metabolic pathways can be created using modern biology tools and this opens up many possibilities.

THERAPEUTIC PROTEINS

Session Chairs: Karen Polizzi (Imperial College), Eli Keshavarz-Moore (UCL), and Michael Hohn  (Merck)

Many therapeutic proteins traditionally consist of a mixture of glycoforms. This has been a barrier for using microbial hosts but can also be viewed as an advantage. A microbial host can be used to make a specific glycoform without the presence of less biologically active glycoforms. Also, speed can be much faster with a microbial host compared to traditional animal cell culture hosts.

BIOFUELS AND BIODERIVED POLYMERS

Session Chairs: Behnam Taidi (CentraleSupelec) and Joel Cherry (Amyris)

We can project many potential answers to our challenge of providing energy without burning fossil fuels by switching to renewable sources for making electricity. However, for air travel, we need a renewable source of biofuel to replace the current fossil fuel based supply.

With advances in synthetic biology and metabolic engineering, we are seeing a vast number of opportunities to manufacture useful polymers in a more sustainable way. Some examples will be given in this session.

Conference Organization

Co-Chairs:

Prof. Eli Keshavarz-Moore , University College London, England
Dr. Barry Buckland, BiologicB, USA

Organizing Committee:

Arindam Bose (Previously Pfizer, now Consultant), USA
Tim Charlebois (Pfizer) USA
Brigitte Gasser  (BOKU) Austria
Akshay Goel (Biologic E) India
Peter Gray  (AIBN, University of Queensland) Australia
Wayne Herber  (Assembly Biosciences), USA
Beth Junker (BioProcess Advantage LLC), USA
Chris Love (Koch Institute at MIT), USA
Gargi Maheshwari (Merck), USA
Gautam Nayer  (BMS), USA
Darren Nesbeth (University College London), UK
Karen Polizzi (IC), UK
Tiffany Rau  (Evonik-Degussa), USA
Natarajan Sethuraman (Previously GlycoFi ; now Consultant), USA
Daniel Smith  (Cobra Biologics), UK
Jim Swartz  (Stanford University), USA
Behnam Taidi  (CentraleSupélec), France

Poster Co-Chairs:

Darren Nesbeth (UCL)
Stefanie Frank (UCL)
Pedro Moura (Merck)

Abstract Submission

One-page abstracts should be submitted as soon as possible and no later than the deadlines noted below.  The abstract should include both the significance of the research as well as results that will be discussed to allow a scientific assessment of the work by the organizers. Please indicate the session for which you are submitting your abstract and whether the abstract should be considered for an oral or poster presentation. Only a limited number of oral presentation slots are available.  Thus all submissions for oral presentations will be considered for both oral and poster.

Deadline for abstracts for oral presentations:                     November 15, 2017
Deadline for abstracts for poster presentations:                December 31, 2017

Please prepared your abstract according to this template: docx or doc.

All abstracts should be submitted electronically and submissions must follow the template provided at this link.

There will be a poster competition for the Best Student Poster and Best Overall Poster.  More details will be announced.

Conference Venue

Nestled in the cottonwood forest on the banks of the Rio Grande, this uniquely New Mexican hotel is located on 500 acres of the Santa Ana Pueblo in central New Mexico; 25 minutes north of the Albuquerque International Airport and 45 minutes south of historic Santa Fe. It was created by the Santa Ana Pueblo Indians to showcase their ancient culture and traditions.

Situated at the base of the Sandia Mountains in New Mexico, the Hyatt Regency Tamaya is a unique destination unlike anything you have probably experienced before.  It combines the beauty and culture of the Southwest with convenience to the Albuquerque Airport.   The hotel has spacious pueblo-style guestrooms, outdoor pools and a golf course surrounded by breathtaking mountain vistas.  Hot air balloon rides with soaring views of these sacred lands are a very popular activity for hotel guests.

The hotel has 350 guestrooms (including 158 kings and 169 queen-doubles).  Each room has a private balcony or patio.  The pueblo-style room accommodations showcase traditional New Mexico designs as they were created with natural materials. Every guest room includes a spacious work area with enhanced lighting and complimentary Wi-Fi. The in-room safes accommodate laptop computers.  Rooms also have bathrobes, in-room refrigerator and coffee-maker, and climate control. Laundry and dry cleaning are available.  The hotel facilities also include a Hyatt Stayfit fitness center,

Albuquerque Information A to Z

Transportation

Albuquerque International Airport, ABQ, is very close to Albuquerque itself, about 5 miles (8 km).  It is 26 miles (43 km) from the Hyatt Regency Tamaya Resort & Spa.  Slightly further away is the Santa Fe Airport, SAF, 42 miles (70 km).  Driving directions from either airport.

Albuqerque Airport Car Rentals           From the Albuquerque airport to hotel–Sunport Shuttle.                         Ground transportation at the Albuquerque airport.

Santa Fe Ground Transportation and Car Rentals

General Information about ECI

Engineering Conferences International (ECI) is a global engineering conferences program, originally established in 1962, that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines.

The format of the weeklong research conference provides morning and late afternoon or evening sessions in which major presentations are made. Available time is included during the afternoons for ad hoc meetings, informal discussions, and/or recreation. This format is designed to enhance rapport among participants and promote dialogue on the development of the meeting. We believe that the conferences have been instrumental in generating ideas and disseminating information to a greater extent than is possible through more conventional forums.

All participants are expected both to attend the entire conference and to contribute actively to the discussions. The recording/photographing of lectures and presentations is forbidden. As ECI conferences take place in an informal atmosphere, casual clothing is the usual attire.

Engineering Conferences International
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