Single-Use Technologies IV: Building the Future

An ECI Conference Series

May 10-13, 2020
Intercontinental Marseille Hotel Dieu
Marseille, France

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About This Conference

Conference Synopsis

Single-Use Technologies IV: Building the Future is the fourth event of an ECI conference series started in 2015 and unique in its aim – to advance knowledge in the fundamental science and engineering underpinning Single-Use Technology (SUT).

The conference will be a 4-day event (May 10 to 13, 2020) in Marseille, France, and will target 100-120 attendees. The conference will have speakers and attendees from industry and academia, single-use final product (e.g., bags, assemblies) manufacturers, film/resin manufacturers as well as keynote speakers from the biopharmaceutical industry, experts in polymers/materials science and manufacturers of novel biomedical devices.

The fourth series of this conference will build on the success of the previous three editions and aim to focus on integration, standardization and facility design challenges for established and emerging applications. Other topics will include sustainability aspects, novel studies on biodegradable materials and plant design for minimal wastage, advances in sensors, soft sensors and their integration within SUT, modelling and optimization tools for the economic, social and environmental assessment of SUT in production facilities.

This conference brings together a multidisciplinary community interested in collaborating openly towards the advancement and adoption of single-use technology in the bioprocessing industry. The organizing committee welcomes the submission of scientific work that is novel and of high quality.

Please click these links to view previous conferences in this series.  2018   2017   2015

Session Descriptions

Session 1 – Novel polymers and Interactions between polymers and biologicals
Co-chairs: Nelly Montenay (Sartorius-Stedim Biotech) and Sheryl Kane (Takeda)

This session will address aspects of polymers in bioprocessing throughout the material lifecycle, from new material development through characterization, and lessons learned during use.

Focus areas include:

  • Novel materials and applications such as sustainable polymers (beginning of SUT life) or other materials, new films, as well as applications such as additive manufacturing/3-D printing
  • Characterization and regulatory considerations such as identification of compounds that affect amino-acids / protein aggregation, and end user expectations around a validation package
  • Impact of material properties such as case studies about a specific property impacting a particular application, or the properties required for more challenging process uses.

Session 2 – Sensors and their integration with single-use technology
Co-chairs: Torsten Mayr (Technical University of Graz) and Jim Furey (PendoTECH)

Sensors are critical to biopharmaceutical manufacturing for process control, data acquisition, PAT in continuous processing that lead to a more efficient manufacturing processes. Single use processes require sensors that are pre-sterilized, ready to use without any calibration and can be disposed of after the process. Ideally, these sensors are suitable for both batch and continuous processes. The scope of this session is to give insights in new developments and advances of sensors for single-use, efforts towards integration in single-use devices, new parameters, miniaturisations, soft sensors, reliability, robustness, and validation approaches for use in a GMP process.

Session 3 – Single-Use advantages in continuous and connected processing
Co-Chairs: Peter Levison (Pall Biotech) and Mark Brower (Merck)

This session will address how SUT have facilitated and supported the development of continuous operation processes for biopharmaceuticals production.

Focus areas will include:

  • The economic case for SUT in continuous processing, for both upstream and downstream operations and end-to-end processing
  • Regulatory and validation considerations and challenges for SUT in continuous processes
  • Innovative solutions in SUT for continuous processes
  • Scale-down approaches for SUT continuous processes

Session 4 – Single-use adoption in emerging applications
Co-chairs: Qasim Rafiq (University College London) and Diego Schmidhalter (Lonza)

This session will focus on the use of single-use technologies in bioprocesses for emerging applications, including vaccines, cell and gene therapy, industrial biotechnology and antibody-drug conjugates. The session will include case studies showcasing the adoption and application of single-use technologies across these bioprocessing sectors, with a focus on the challenges and opportunities associated with their integration. In some instances, these sectors rely exclusively on single-use technologies (e.g. patient-specific gene therapies), and this session will highlight how single-use technology can accelerate the quest for speed and flexibility in this space. This session will provide an evaluation of how single-use technologies have been implemented, with a specific focus on upstream/downstream process unit operations and end-to-end bioprocessing. It will also explore the future requirements and perspectives to ensure successful integration of single-use technologies for the manufacture of 21st century biological products.

Session 5 – Single-use performance and learning from other industries
Co-Chairs: Jeffrey Carter (GE Healthcare) and Wang Xueyuan (Roche Genentech)

Single-use technologies (SUT) provide many benefits as compared to their traditional stainless steel counterpart, i.e., reduced cost of initial capital investment, decreased cleaning validation, added manufacturing flexibility, and faster time to market. At the same time, SUT present challenges in areas of such as equipment qualification, process validation, and waste management.

This session will focus broadly on various aspects SUT performance.  Topics may include performance of SUT vs stainless steel (from upstream cell culture to downstream purification and aseptic fill), advancement of new technologies, standardization work on SUT (from testing validation to leak investigation), and measures to improve SUT robustness, SUT best practices, and learnings from other industries, e.g., the food and beverage industry, and (hospital) waste management, such as recycling or incineration  for energy (end of SUT life).

Session 6 – How to integrate single use in facility design
Co-chairs: Dave Wolton (PM group) and Vincent Kelley (GSK)

This session will explore the influence of single use technology in Biopharmaceutical manufacturing facility design, by looking at several unique case studies within our industry.  Learn how single use and stainless steel hybrid facilities can optimize multi-product flexibility and operational efficiency.  Explore examples of where single use systems have meaningfully reduced capital costs, footprint and operational expenses.  Explore how single use technology could be leveraged in cutting edge continuous production facility design.

Abstract Submissions

One-page abstracts should be submitted as soon as possible and no later than the deadlines noted below. The abstract should include both the significance of the research as well as results that will be discussed in order to allow a scientific assessment of the work by the organizers. Please indicate the most relevant session topic for which you are submitting your abstract and whether the abstract should be considered for an oral or poster presentation.

The specific topics are (sessions are described above):

Session 1 – Novel polymers and Interactions between polymers and biologicals

Session 2 – Sensors and their integration with single-use technology

Session 3 – Single-Use advantages in continuous and connected processing

Session 4 – Single-use adoption in emerging applications

Session 5 – Single-use performance and learning from other industries

Session 6 – How to integrate single use in facility design

Only a limited number of oral presentation slots are available. Thus all submissions for oral sessions will be considered for both oral and poster presentation.

All abstracts should be submitted electronically and submissions must follow the template provided at this link.

Deadline for abstracts for oral presentations:                   December 31, 2019
Deadline for abstracts for poster presentations:               December 31, 2019

Awards will be presented for the overall best poster and for the top three student posters.

Conference Organization


Magali Barbaroux, Sartorius-Stedim, France
Weibing Ding, GSK, USA
Martina Micheletti, University College London, UK

Steering Committee for Single-Use Technologies IV

Ruben Carbonell, North Carolina State University
Cory Card, GE Healthcare
Regine Eibl-Schindler, Zurich University of Applied Sciences
Jeffrey Johnson, Merck
Beth Junker, BioProcess Advantage LLC
Sally Kline, Genentech-Roche
Gary Lye, University College London
Ekta Mahajan, Genentech-Roche
Robert Repetto, Pfizer

Sponsorship Levels

Please click HERE to view the levels of sponsorship.

Conference Venue

Marseille is the oldest city in France. A Greek settlement, founded in the 7th century BC, then called Massilia, Marseille was seized by the Romans in 49 BC.  It became the “Gateway to the West” for most Oriental trade.  France’s largest port and lively second largest city has close links with the Middle East and North Africa.  It claims 300 days of sunshine per year

Narrow stepped streets, quiet squares, and fine 18th century facades contrast with the bustle of Boulevard Canebiére and the Cité Radieuse, Le Corbusier’s postwar radical housing complex.  The old harbor now only handles small boats, but its daily fish market is renowned.  The intense smell of fish and salty sea air contribute to making this experience engaging to the senses.  Large cruise ships dock at Léon Gourret Pier, approximately five kilometers north.

The defining symbol of Marseille towers on a hilltop 154 meters above the city, with the gilded statue of the Virgin Mary stretching skywards.  The views are simply stunning.  One can either take a shuttle for convenience or embark on a just-under-an-hour-long hike up from the old port.

Saint Victor Abbey is Marseille’s oldest church.  The abbey was built by the graves of Marseille’s first martyrs.  Throughout history, the building was used as a church, prison, warehouse and barracks.

Marseille has many excellent museums.  Those in the old harbor include the Roman Docks Museum, situated on the site of a Roman docks warehouse discovered after World War II.  It contains a range of impressive artefacts discovered during the reconstruction of the Old Harbor.  One of its primary attractions are the “dolia” – large ceramic containers once used to store oils and wines.

The Marseille History Museum is an interesting and well-visited museum with historical and archeological artefacts dating back to the city’s founding times.   The Palais Longchamp is an extraordinary, majestic building right in the middle of the city that takes you years back in time with its ornamental staircases and large fountains.  The building houses the Musée des Beaux-Arts and the Natural History Museum.

Splendidly situated on a hillside above the Vieux Port, this colorful neighborhood is the historic center and cultural heart of Marseille. Le Panier is Marseille’s oldest quarter, inhabited since antiquity when the ancient Greeks settled here in 600 BC. With its steep, narrow winding streets and quaint pastel buildings, this quarter offers a glimpse into the charming personality of Marseilles. Once a working class neighborhood, Le Panier is now gentrified, but still has a fascinating multiethnic and artistic character. You will find plenty of authentic Algerian cuisine, local artisan boutiques, gourmet food shops, and art galleries. This quarter is also a residential neighborhood, and the typical houses with shuttered window and lines of laundry provide evidence of the families who live there.

The Marseille Tourism website,, provides a wealth of information about this vibrant city and it is highly recommended that you check it out.

InterContinental Marseille – Hotel Dieu

Housed in a listed historical monument, having served as the city’s primary hospital for over eight hundred years, this elegant hotel opened in 2013.  Offering an inimitable view of Marseille, the InterContinental Marseille-Hotel Dieu, is a most majestic encounter with the city and Provence.  It is perfectly located, overlooking the Vieux Port, right beside the oldest district in Marseille known as the Panier.  The hotel boasts a very beautiful terrace from which one can admire the Vieux Port.

The remains of a 12th century chapel are buried beneath the hotel’s gardens. A Roman mosaic dating from the 1st century A.D. can be seen in the Espace Culturel (on the ground floor).  A sustainable pilot project, the InterContinental Marseille – Hotel Dieu is the first hotel ever to be restructured subject to an environmental quality certification. This certification requires scrupulous monitoring of stringent specifications, especially in the choice of building materials, energy and water management, visual comfort, acoustics, and in the quality of air and water.

Link to hotel brochure:  Intercontinental Marseille Hotel Dieu  1 Place Daviel : Marseille ,13002, France

36 Hours in Marseilles – The New York Times

Conference Fees and Registration

We expect to open registration by the end of 2019 when the preliminary program will be available.  The estimated conference fee (including registration; single hotel room for nights of May 10, May 11, and May 12; meals, coffee breaks and gala dinner) is expected to be US$2395, dependent on exchange rates.

General Information about ECI

Engineering Conferences International (ECI) is a global engineering conferences program, originally established in 1962, that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines.

The format of the weeklong research conference provides morning and late afternoon or evening sessions in which major presentations are made. Available time is included during the afternoons for ad hoc meetings, informal discussions, and/or recreation. This format is designed to enhance rapport among participants and promote dialogue on the development of the meeting. We believe that the conferences have been instrumental in generating ideas and disseminating information to a greater extent than is possible through more conventional forums.

All participants are expected both to attend the entire conference and to contribute actively to the discussions. The recording/photographing of lectures and presentations is forbidden. As ECI conferences take place in an informal atmosphere, casual clothing is the usual attire.

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