Vaccine Technology VI

an ECI Conference Series

June 12-17, 2016
Grande Real Santa Eulalia Hotel
Albufeira, Portugal 

Call for Abstracts!         Final Program with posters

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About This Conference

This conference series addresses technical and scientific issues in the development and manufacturing of vaccines.  It will also discuss broader issues related to vaccine development and access that will be of interest to institutional and academic participants.  Emphasis will be particularly placed on emerging diseases and developing world.

Oral Session Descriptions

Session I: Break Through Developments in Vaccinology

Chairs: Florian Krammer, The Mount Sinai Hospital, USA, and Haru Pujar, Moderna Therapeutics, USA

This session will highlight new basic research findings and enablers of vaccine development.  Examples could be new immunology discoveries relevant for vaccine technology, new clinical assays/correlates, new vectoring (nanoparticles) or new adjuvants to steer immune response.

Session II: Issues and Case Studies in Process Development

Chairs: Udo Reichl, Max Planck, Germany and Charles Lutsch, Shantha Biologics, India

Production of efficacious and safe vaccines poses significant challenges in upstream and downstream processing as well as in formulation. To reduce costs per dose and to cope with ever increasing demands, this session will focus on further steps towards process intensification to increase product yields, the establishment of platform technologies to speed up process development, advances in process analytics, and the use of disposables for campaign-based vaccine manufacturing. Examples from mature markets and developing Countries will be highlighted.

Session III: Formulating and Delivering Vaccines

Chairs: David Volkin, Kansas University, USA

“I have a great candidate for a vaccine that will solve an unmet medical need….  But how do I get it tested to demonstrate its value?”  This session deals with the different steps that need to be taken in order to bring a concept to the first clinical trial, from the definition of the vaccine form (formulation, route of administration) to the various steps that need to be taken before entering into humans. Each vaccine candidate is unique and will require specific approach, nonetheless a common path can be defined and followed to maximize the chances of reaching a fast go/no go decision. Those paths will be discussed, including from how to select the formulation and validate its choice, to discussing the new emerging delivery technologies that are being brought to the field of vaccines. Finally, this session will be concluded by a discussion among the speakers on the various avenues, their benefit and challenges.

Session IV: Vaccine Characterization and Analytics

Chairs: Linda Lua, University of Queensland, Australia, and Indresh Srivastava, Protein Sciences, USA

Vaccine characterization applies to all phases of vaccine development, final release vaccine product and process consistency during manufacture. It encompasses all in vitro and in vivo assays to evaluate the biological, chemical and physical properties of a vaccine. In-depth characterization of vaccines provides an understanding on the function, potency and toxicity issues, and improves vaccine efficacy and safety. In addition, bio-analytical characterization plays a critical role in establishing comparability of the product produced with process, scale and site changes. This session will focus on testing strategies and case studies highlighting the pivotal role of analytical characterization in vaccine development, licensure, and post-licensure life cycle management.

Session V: Therapeutic Vaccines

Chairs: Laurent Huemau, Inovio, USA, and Tony Hitchcock, Cobra Biologics, United Kingdom

The recognition of the key role of the immune system and of viruses in a wide range of diseases is increasing every day.  In this session, new approaches for the development of therapeutic vaccines will be discussed. Of special interest is the identification of new immunological targets, therapies for oncology and addictions, the role of tolerization, and others.

Session VI: Getting Vaccines to the Market: Case studies

Chairs: Rebecca Sheets, Grimalkin Partners, USA and Danilo R. Casimiro, Aeras, USA

Session VII: New Challenges and Technologies in Vaccine Development

Chairs: Odile Leroy, European Vaccine Initiative, Germany, and Albert Price, Medimmune, USA

The next wave of vaccines to be developed will need to overcome new challenges, such as rapidly responding to emerging pathogens, eliciting effective immune responses against “difficult” targets that evade the immune system, and prevention and treatment of various diseases including non-communicable diseases. To address these challenges, the application of multiple new technologies to vaccine strategies will be required. Our quickly growing understanding of both the immune system and the molecular biology of pathogens, pathogenesis and risk factors, all enable new strategies for prevention and treatment. New vectors, synthetic biology, and specific immune modulation are examples that will play prominent roles for the vaccinology of the 21st century. This session will feature examples of new technologies and approaches that will address major challenges in vaccinology.

Session VIII. One World, One Health

Chairs: Monica Dias Figueiredo, Merial, USA, Ab Osterhaus, University of Veterinary Medicine Hannover, Germany, and Juan Garza, UNAM, Mexico

The vast majority of emerging and re-emerging pathogens in humans is of animal origin.  Most of this growing number of threats has its origin in wildlife, while humans are exposed either directly or through indirect domestic animal contacts.  Effective and economical ways of protecting mankind from emerging diseases are best based on combatting zoonotic pathogens at the animal source.  The “One Health” concept creates awareness of the major opportunities that exist to protect public health through policies aimed at controlling these pathogens at the level of their animal hosts, or more specifically, at the interface between humans, animals and their environments.  Implementation of these policies places those who have regular contacts with domestic animals, like owners, handlers and veterinarians, in the front line together with those who regularly come into contact with wildlife and their environment.  This session will highlight the importance of the integration between medical and veterinary disciplines within the One Health concept.

These topics will be applicable to prophylactic and therapeutic vaccines as well as those for defense and emerging diseases.  Click HERE for a printable version.

Confirmed Keynote Speakers

Ian Frazer, University of  Queensland, Australia
Katey Owen, Bill & Melinda Gates Foundation, USA
Michael Kurilla, National Institute of Allergy and Infectious Diseases (NIAID), USA
Johan Van Hoof, Janssen Research and Development, Belgium

Conference Organization

Conference Co-Chairs

Laura Palomares, UNAM, Mexico
Manon Cox, Protein Sciences Corporation, USA
Tarit Mukhopadhyay, University College London, UK
Nathalie Garçon, BIOASTER Technology Research Institute, FR

Poster Session Chairs

Ruth Pastor, Instituto de Biotecnología, UNAM, México
Valerie Mermall, Protein Sciences Corporation, USA
Antonio Roldao, IBET, Portugal

Organizing Committee

Paula Alves, IBET; Rick Bright, BARDA; Barry Buckland, BiologicB; Fred Cassels, NIAID; Jose A. Chabelgoity, Instituto de Higiene; Anne de Groot, EpiVax; Monica Dias Figuereido, Merial; Quico Godia, UABarcelona; Johan V. Hoof, Janssen (J&J); Amine Kamen, McGill University, Florian Krammer, Icahn School of Medicine at Mount Sinai; Linda Lua, University of Queensland; Charles Lutsch, Sanofi/Shanta; Bob Nordgren, Merial; Al Price, Medimmune; Hari Pujar, Moderna Therapeutics; Udo Reichl, Max Planck Institute; Guus Rimmelzwaan, Rotterdam University; Steve Rockman, CSL; Ingrid Scully, Pfizer; Rebecca Sheets, Grimalkin Partners; Sergio Valentinotti, Liomont; Vidadi  Yusibov, Fraunhofer

Abstract Submission

Deadline for abstracts for oral presentations:               February 28, 2016

Deadline for abstracts for poster presentations:          February 28, 2016

Abstracts of approximately 300 words should be submitted as soon as possible and no later than the deadlines noted above.  The abstract should include both the significance of the research as well as results that will be discussed in order to allow a scientific assessment of the work by the organizers.  Please indicate the session for which you are submitting your abstract, or else select “poster presentation”.

For session information, see the Oral Session Descriptions.

Only a limited number of oral presentation slots are available. Thus all submissions for oral sessions will be considered for both oral and poster presentation.

All abstracts should be submitted electronically and submissions must follow the template provided at this link.

Poster Size:   Height x Width (1.5 meters x 1 meter)

 

Major Sponsors

Please click on the logo to view the website.

Conference Venue

Situated in the extreme south of Portugal, the Algarve was the final piece of territory to be conquered from the Moors by the Portuguese King Dinis in 1292. Traces of Moorish presence are still seen in its architecture – terraces, chimneys and whitewashed houses. The name Albufeira has its etymological root in the Arabic, a result from the maritime trade relations with North Africa. Al-Buhera means “Sea Castle,” which may reflect the existence of a fort in the region. The great 1755 Lisbon earthquake destroyed the town of Albufeira, destroying activity which was only resumed in the mid- 19th century. For years the export of fish and several nuts were the main economic sources of the region. Tourist activity arose in the 1960s.

The Algarve, known for its idyllic beaches and ideal temperatures, is just three hours from Lisbon by motorway. In the northern part of the Algarve, the hills of Espinhaço de Cão, Monchique and Serra do Caldeirão shelter the coast from strong winds. This brightly colored region, with its fig and carob trees, orange groves and almond trees in blossom complement the rich green vegetation and fertile land so characteristic of the whole of the northern Algarve. In strong contrast with the north, the southern Algarve is a coastal zone with long stretches of sandy beach, separated by extraordinary rugged cliffs and fantastic grottoes.

The town of Albufeira is a cosmopolitan town rich in historical and cultural sites. Notable attractions include the 19th Century Clock Tower (a symbol of the city), and the charming 18th Century parish church built in neo-classical style. The remains of one of the towers of the old Castle Wall can be explored as can the Arch of the Travessa da Igreja Velha, a beautiful example of Arab architecture.

Other nearby places of interest include Castro Marim (one can visit the dirt-built Castle), the Old Town of Faro, the Ilhas da Ria Formosa (National Park), the old town of Lagos with its old slave market, Loulé, Paderne (last Moorish castle ruin – one of the battlements featured on the Portuguese flag), Vila do Bispo, Sagres (the western most point of Europe and strongest lighthouse in Europe), and Silves where one can visit the medieval castle and old Moorish town.

The following web sites contain useful information:

Tourism: https://www.visitportugal.com/en, www.albufeira.com/, www.visitalgarve.pt (Algarve culture, tradition, nature and landscape, Albufeira, cultural calendar, golf, sports and adventure)

Weather:  High temperatures in the Algarve at this time of year (June) average around 25°C (77°F), and the lows are about 17°C (63°F).  Bring appropriate clothing and sun protection.  Keep in mind that you may want a sweater, as conference rooms tend to be chilly at the beginning of the sessionwww.meteo.pt

Conference Hotel:  The conference will be held at the Grande Real Santa Eulalia Hotel in Albufeira, Algarve, Portugal. The resort has state of the art conference facilities and has hosted numerous meetings. It boasts 1,500 square meters of meeting space, including a large ballroom area, five breakout rooms, a business centre and two large foyers. The hotel offers free wireless internet in the conferences area and guest rooms. There is a Thalasso Spa with a fitness room, sauna and heated indoor interactive swimming pool, four tennis courts, and four outdoor heated swimming pools (including a salt water pool). A small gift shop is on site. Dry cleaning and laundry services are available. Family amenities include a children’s pool, babysitting and supervised activities. Parking is free. There is direct access to the Santa Eulalia beach and multiple golf courses in the area. The hotel is also a short distance from Maria Luisa Beach and Oura Beach.

The bedrooms have satellite television, air conditioning, climate control, safes and minibars.

Transportation

The Municipality of Albufeira lies on the southern coast of Portugal, in the Algarve. As a tourist destination, Albufeira offers good air, rail and road links. The nearest airport is Faro International Airport, 35Km from Albufeira, which is served by various national and international links.

The Algarve is served by two main roads which extend parallel along the southern coast, the A22 Motorway (Castro Marim to Vila do Bispo) and the National Road 125 (Vila Real de Sto. António to Sagres), both passing close to Albufeira, linking it with Faro.

The road link between Albufeira and Lisbon is the A2 SUL Motorway and by the IP1, and the rail link is the Lisbon-Faro line. The nearest train station is 11Km from the hotel.

The hotel offers a free shuttle to Albufeira.

Conference Fees and Registration

Conference Fees

All conference fees are inclusive. They include registration, accommodations (Sunday, Monday, Tuesday, Wednesday and Thursday nights), all meals with the exception of dinner on Tuesday, excursion, taxes, and gratuities from the welcome drink and dinner on Sunday through breakfast on Friday. Incidental fees (telephone calls, faxes, spa, laundry, etc.) are billed to your personal account by the hotel.

ALL PARTICIPANTS (INCLUDING MEMBERS OF THE ORGANIZING COMMITTEE AND INVITED SPEAKERS) ARE REQUIRED TO REGISTER.

The conference fees are:

Register on or before May 15, 2016 Register after May 15, 2016
Participant (single occupancy or sharing room with a guest; guest fee additional) US $2,330.00 US $2,530.00
Participant (sharing a room with another participant) US $1,955.00 US $2,155.00
Bona fide Graduate Student (sharing a room with another student) (Those in this category must send proof of current status – copy of current Student ID can be faxed to 1-212-514-6030 or emailed to Kathy@engconfintl.org) US $1,520.00 US $1,720.00
**Fees for Guest/accompanying person sharing bedroom with single occupancy participant. (Includes all conference included meals as well as the conference excursion) US $635.00 US $635.00
**Fees for Guest/accompanying person sharing bedroom with single occupancy participant. (Bed and Breakfast only) US $60.00 US $60.00

If you plan to bring children to the conference, please contact ECI (info@engconfintl.org) for pricing.

Pre/Post Conference Hotel Registration:  If you plan to arrive before May 8th or stay after May 13th, you must make separate room reservations directly with the hotel.  Go to THIS PAGE and click on the appropriate conference to access the form for the hotel.

Conference Registration

You will need a login name and password to register for ECI conferences through our online system. If you have been a recent participant at an ECI conference or have submitted an online application or request for information about an ECI Conference, you may already have an account with us. If you know your login information, please use it.

If you are not sure whether you already have a login and password, please click on automated password retrieval and enter your e-mail address before creating a new account. If we don’t have a valid email address on file for you, a pop up window will appear stating that no records were found. Click “OK” and then follow the instructions to create a new account.

If you have any questions or experience any difficulties, please email tressa@engconfintl.org.

Special Notes for Payment

Special Notes and Payment Instructions

We suggest that you register as soon as possible to be certain that you will have a hotel room at the conference rate.  Late registrations will be accepted on a space available basis.

All participants are encouraged to register before May 15, 2016.  There is a discounted price for registering before this date and hotel space cannot be guaranteed for registrations received after this date.  Your registration is not officially confirmed until we receive payment of the amount due.  ECI reserves the right to cancel your room registration if payment is not received. Your invoice/receipt will automatically be e-mailed upon of receipt of your registration.

Because of contractual guarantees made with the hotel for room and meal functions, no shows, late arrivals, missed meals and early departures cannot receive fee adjustments.  If you have a disability and may require accommodation in order to participate fully in this conference, please indicate this when you register. An ECI representative will contact you to discuss your specific needs. If you have special dietary requirements (e.g., vegetarian or a food allergy), please make a note on your registration.  The chef needs to know this information in advance if we are to accommodate you. ECI will attempt to accommodate special requests such as Kosher or Halal meals, but such meals may not be available at all conference sites. Any additional costs for special meal requests must be paid by the participant to ECI.

Payment must be made by credit card (Visa, MasterCard, Amex), check or money order drawn on a U.S. bank in U.S. dollars, payable to ENGINEERING CONFERENCES INTERNATIONAL. Checks or money orders in any other currencies are NOT ACCEPTABLE.  Payment is made on the web site except for those who are sending payment by wire transfer or have a purchase order from their company/institution.

WIRE TRANSFER PAYMENT: If you are planning to make payment by wire transfer, please contact ECI for the bank information. You must add $30 to cover ECI bank charges. Please reference your full name and the conference title.  Either fax a copy of your bank transfer papers to ECI (Fax: +1-212-514-6030) or email a scanned copy to kathy@engconfintl.org.  This is very important – otherwise it is extremely difficult to trace your payment and you may not receive a receipt prior to the conference.

Cancellation Policy: Cancellation must be received by ECI in writing at least 28 days prior to the start of the conference in order for a full refund (less a processing fee) to be considered. The ECI auditors require that refunds for all conference cancellations be processed after the conference so that the necessary back-up information (e.g., hotel list of those in-house) can be attached to the refund request and ECI can verify that the hotel has not charged a cancellation fee.

Cancellation fees:

  • Cancellations received more than 28 days prior to the conference start date are subject to a processing fee of 4% of the total fee, plus any direct expenses incurred by ECI.
  • Cancellations received 15 – 28 days prior to the conference start date are subject to a $250 cancellation fee plus any direct expenses incurred by ECI.
  • Cancellations received 8 – 14 days prior to the conference start date are subject to a $500 cancellation fee plus any direct expenses incurred by ECI.
  • No refunds will be issued for cancellations received less than 7 days prior to the conference start date.
  • No refunds will be issued due to inclement weather or travel disruptions/cancellations.

Registrations can be transferred without incurring any penalty or cancellation fee.

Denied or delayed visa

If a participant is forced to cancel due to a denied or delayed entry visa, ECI will issue a full refund provided that ECI has been notified of a potential visa issue at least four weeks prior to the conference start date.

Change of payment method

If an attendee who has already paid the conference fee with a credit card requests that the fee be refunded to that card so that it can be paid in a different manner (e.g., charged to an alternate credit card, or paid via check or bank transfer), a processing fee of 4% of the total fee amount will apply.

Disclaimer

It may be necessary for reasons beyond the control of ECI to alter the content and timing of the program or the identity of the speakers. In the unfortunate circumstance that an event is cancelled, ECI is not liable for any costs incurred by participants in connection with their attendance.

Smoking is prohibited at ECI conferences and conference functions.

Should you have specific questions regarding your registration, please contact Kathy Chan (Kathy@engconfintl.org).

Register Now!

Please click HERE to register for this conference.

Final Program

Please click HERE to view the final program and posters.

General Information

Engineering Conferences International (ECI) is a global engineering conferences program, originally established in 1962, that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines.

The format of the weeklong research conference provides morning and late afternoon or evening sessions in which major presentations are made. Available time is included during the afternoons for ad hoc meetings, informal discussions, and/or recreation. This format is designed to enhance rapport among participants and promote dialogue on the development of the meeting. We believe that the conferences have been instrumental in generating ideas and disseminating information to a greater extent than is possible through more conventional forums.

All participants are expected both to attend the entire conference and to contribute actively to the discussions. The recording of lectures and presentations is forbidden. As ECI conferences take place in an informal atmosphere, casual clothing is the usual attire.

The Engineering Conferences International conferences calendar and other information can be found on the ECI web site: www.engconfintl.org

Engineering Conferences International
32 Broadway, Suite 314, New York, NY 10004
T: 1-7212-514-6760 – F: 1-212-514-6030

info@engconfintl.org – www.engconfintl.org

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